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巴西南部年轻人哮喘死亡率的趋势。

Trends in asthma mortality in young people in southern Brazil.

作者信息

Chatkin J M, Barreto S M, Fonseca N A, Gutiérrez C A, Sears M R

机构信息

The Medical School, Catholic University of Rio Grande do Sul, Porto Alegre, Brazil.

出版信息

Ann Allergy Asthma Immunol. 1999 Mar;82(3):287-92. doi: 10.1016/S1081-1206(10)62610-5.

Abstract

BACKGROUND

Mortality from asthma increased and is now declining in some countries, but little is known about these trends in South America.

OBJECTIVE

We aimed to assess trends in mortality from asthma in southern Brazil in children and young adults.

METHODS

Death certificates of 425 people in the state of Rio Grande do Sul aged between 5 and 39 years in whom asthma was reported to be the underlying cause of death during the period 1970 to 1992 were reviewed. Population data were available in 10-year age groups. Testing for trends in mortality rates was conducted using linear and log-linear regression procedures.

RESULTS

Asthma mortality rates in the age groups 5 to 19 and 20 to 39 years ranged between 0.04 and 0.39/100,000 and 0.28 to 0.75/100,000, respectively, and were nonuniformly distributed over the study period. The mean annual increase in rate in 5- to 19-year olds was +0.01 (95% CI 0.003 to 0.016), an average annual percentage increase of +6.8% (95% CI 3% to 11%), with a total increase of 352% between 1970 and 1992. This increase was not due to a shift in labeling from bronchitis to asthma. In the 20 to 39-year age group, asthma and bronchitis mortality rates showed no trend to increase or decrease.

CONCLUSIONS

Asthma mortality in southern Brazil is low, but rose significantly between 1970 and 1992 in the 5 to 19-year age group. This trend differs from that found in other states of Brazil and several other Latin American countries. Reasons for this difference remain unclear.

摘要

背景

哮喘死亡率有所上升,目前在一些国家呈下降趋势,但南美洲的这些趋势鲜为人知。

目的

我们旨在评估巴西南部儿童和青年哮喘死亡率的趋势。

方法

回顾了南里奥格兰德州425名年龄在5至39岁之间的死亡证明,这些人在1970年至1992年期间哮喘被报告为潜在死因。可获得10岁年龄组的人口数据。使用线性和对数线性回归程序对死亡率趋势进行检验。

结果

5至19岁和20至39岁年龄组的哮喘死亡率分别在0.04至0.39/10万和0.28至0.75/10万之间,并且在研究期间分布不均匀。5至19岁儿童的年平均增长率为+0.01(95%CI 0.003至0.016),年平均百分比增长率为+6.8%(95%CI 3%至11%),1970年至1992年期间总增长率为352%。这种增长并非由于诊断从支气管炎改为哮喘。在20至39岁年龄组中,哮喘和支气管炎死亡率没有上升或下降的趋势。

结论

巴西南部哮喘死亡率较低,但在1970年至1992年期间,5至19岁年龄组显著上升。这一趋势与巴西其他州和其他几个拉丁美洲国家的情况不同。这种差异的原因尚不清楚。

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