Wettstein A
Stadtärztlicher Dienst Zürich.
Ther Umsch. 1999 Feb;56(2):69-73. doi: 10.1024/0040-5930.56.2.69.
The prevalence of dementia varies according to the definitions used but shows always an exponential increase with age, a doubling by every five years increase from 60-95 years. Due to the aging of the baby boom generation a doubling of dementia prevalence in the next 50 years is to be expected. Alzheimer's disease is the most frequent cause of dementia. Combinations with vascular, Lewybody, frontotemporal and other causes of dementia are much more frequent than first considered. They all give rise to severe dementia despite only mild Alzheimer changes in the brain. However, a therapeutic response may be expected from cholinergic therapy. Since this pharmacotherapy of dementia only leads to a limited delay of 6-10 months in the progression of dementia, combinations with psychosocial measures such as caregiver-education and care-planning are necessary. We therefore need centers of excellence, such as memory clinics or psychogeriatric counselling centers throughout Switzerland.
痴呆症的患病率因所采用的定义而异,但始终呈现随年龄呈指数增长的趋势,从60岁至95岁,每增加五岁患病率就会翻一番。由于婴儿潮一代的老龄化,预计未来50年痴呆症患病率将翻番。阿尔茨海默病是痴呆症最常见的病因。与血管性、路易体、额颞叶及其他痴呆病因的合并情况比最初认为的更为常见。尽管大脑中仅有轻度的阿尔茨海默病变,但它们都会导致严重的痴呆症。然而,胆碱能疗法可能会带来治疗反应。由于这种痴呆症药物疗法仅能在痴呆症进展过程中有限地延迟6至10个月,因此有必要将其与心理社会措施相结合,如照顾者教育和护理规划。因此,我们在瑞士各地需要卓越中心,如记忆诊所或老年精神病咨询中心。