一些与曲通WR-1339在大鼠肝细胞中蓄积相关的细胞变化。
Some cellular changes associated with triton WR-1339 accumulation in rat hepatocytes.
作者信息
Trout J J, Viles J M
出版信息
Virchows Arch B Cell Pathol. 1978 Oct 16;28(3):279-85. doi: 10.1007/BF02889077.
PMID:100962
Abstract
Electron microscopic morphological and cytochemical techniques were used to follow the sub-cellular events that accompanied Triton WR-1339 accumulation in hepatocytes. Localization of two lysosomal enzymes, acid phosphatase and aryl sulfatase, clearly established the lysosomal nature of the Triton WR-1339 containing electron-lucid structures that appear in hepatocytes following treatment with this compound.
摘要
运用电子显微镜形态学和细胞化学技术追踪伴随曲拉通WR - 1339在肝细胞中蓄积的亚细胞事件。两种溶酶体酶，酸性磷酸酶和芳基硫酸酯酶的定位，明确证实了在用该化合物处理后出现在肝细胞中的含曲拉通WR - 1339的电子透明结构的溶酶体性质。
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