Hirano H, Tomura N, Okane K, Watarai J, Tashiro T
Department of Radiology, Akita University School of Medicine, Japan.
J Comput Assist Tomogr. 1999 Mar-Apr;23(2):280-2. doi: 10.1097/00004728-199903000-00019.
Bulimia nervosa is an eating disorder of which characterized psychopathological symptoms are a recurrent episode of binge eating. The changes in cerebral blood flow (CBF) in a patient with bulimia nervosa between his or her different eating phases are presented. CBF was measured quantitatively by means of single photon emission computed tomography using I-123 N-isopropyl-p-iodoamphetamine. CBF of the global brain during a binge-eating phase was higher than that during an anorexic state phase. In the anorexic state, the CBF in the temporal, parietal, and occipital lobes on the right side was lower than that on the left side. In the binge-eating state, a lack of laterality between the right and left cerebral hemispheres was found. This finding suggests that cerebral activity differs between the two phases, and that asymmetry is dependent of the eating state.
神经性贪食症是一种饮食失调症，其特征性的精神病理症状是反复出现的暴饮暴食发作。本文呈现了一名神经性贪食症患者在不同进食阶段的脑血流量（CBF）变化。通过使用I-123 N-异丙基-p-碘安非他明的单光子发射计算机断层扫描定量测量CBF。暴饮暴食阶段的全脑CBF高于厌食状态阶段。在厌食状态下，右侧颞叶、顶叶和枕叶的CBF低于左侧。在暴饮暴食状态下，发现左右大脑半球之间缺乏偏侧性。这一发现表明两个阶段的大脑活动不同，且不对称性取决于进食状态。
