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螨过敏原的鉴定与定量

Identification and quantification of mite allergens.

作者信息

Luczynska C M

机构信息

Department of Public Health Sciences, Guy's, King's and St Thomas' School of Medicine, London, UK.

出版信息

Allergy. 1998;53(48 Suppl):54-7. doi: 10.1111/j.1398-9995.1998.tb04998.x.

Abstract

Allergens from the house dust mite are ubiquitous in house dust. Exposure to these allergens can cause acute symptoms in patients who are sensitized to house-dust mite and have asthma or other allergic diseases, such as rhinitis or atopic dermatitis. It is not clear how much mite-allergen exposure is a risk factor for the development of sensitization or for triggering acute symptoms. Therefore, it is important to be able to quantify accurately the amount of mite allergen present in the indoor environment in order to carry out studies to identify risk factors for exposure, to investigate exposure-response effects, and to monitor the progress of allergen-reducing regimens.

摘要

屋尘螨过敏原在屋尘中普遍存在。对于对屋尘螨敏感且患有哮喘或其他过敏性疾病(如鼻炎或特应性皮炎)的患者,接触这些过敏原可引发急性症状。目前尚不清楚接触多少螨过敏原会成为致敏或引发急性症状的危险因素。因此,能够准确量化室内环境中存在的螨过敏原量,对于开展研究以确定接触危险因素、调查接触-反应效应以及监测过敏原减少方案的进展情况至关重要。

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