KR025，一种来自黄色粘球菌的新型细胞毒性化合物。
KR025, a new cytotoxic compound from Myxococcus fulvus.
作者信息
Ahn J W, Woo S H, Lee C O, Cho K Y, Kim B S
机构信息
Korea Research Institute of Chemical Technology, P.O. Box 107, Taejon 305-600, Korea.
出版信息
J Nat Prod. 1999 Mar;62(3):495-6. doi: 10.1021/np9804233.
PMID:10096868
Abstract
A new bithiazole, KR-025 (1), was isolated from Myxococcus fulvus. Its structure was elucidated by spectroscopic analysis. In addition to 1, the strain produced relatively large quantities of a second, closely related antibiotic, myxothiazol. These compounds demonstrated potent cytotoxicity against human tumor cells.
摘要
一种新的双噻唑，KR-025（1），从黄色粘球菌中分离得到。其结构通过光谱分析得以阐明。除了1之外，该菌株还产生了相对大量的第二种密切相关的抗生素——粘噻唑。这些化合物对人类肿瘤细胞显示出强大的细胞毒性。
Zotero 插件