托利卟啉J和K，来自蓝藻结节颤藻的另外两种卟啉类代谢产物。
Tolyporphins J and K, two further porphinoid metabolites from the cyanobacterium Tolypothrix nodosa.
作者信息
Prinsep M R, Patterson G M, Larsen L K, Smith C D
机构信息
Department of Chemistry, University of Waikato, Private Bag 3105, Hamilton, New Zealand.
出版信息
J Nat Prod. 1998 Sep;61(9):1133-6. doi: 10.1021/np970566+.
Two new porphinoids, tolyporphins J (1) and K (2), have been isolated from the terrestrial cyanobacterium, Tolypothrix nodosa (HT-58-2) and identified by NMR and mass spectral analysis. The activities of tolyporphins J and K in cell sensitization and drug accumulation assays for multidrug resistance (MDR) reversal were compared with those of tolyporphin A. Unusual NMR spectroscopic shifts were observed for tolyporphin J (1) in CDCl3.
从陆生蓝细菌结节颤藻（HT - 58 - 2）中分离出两种新的卟啉类化合物，即托利卟啉J（1）和K（2），并通过核磁共振和质谱分析对其进行了鉴定。将托利卟啉J和K在多药耐药性（MDR）逆转的细胞致敏和药物积累试验中的活性与托利卟啉A的活性进行了比较。在CDCl3中观察到托利卟啉J（1）有不寻常的核磁共振光谱位移。
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