Petrossian E, Reddy V M, McElhinney D B, Akkersdijk G P, Moore P, Parry A J, Thompson L D, Hanley F L
Division of Cardiothoracic Surgery, University of California, San Francisco, CA, USA.
J Thorac Cardiovasc Surg. 1999 Apr;117(4):688-96. doi: 10.1016/S0022-5223(99)70288-6.
Among the modifications of the Fontan operation, the extracardiac approach may offer the greatest potential for optimizing early postoperative ventricular and pulmonary vascular function, insofar as it can be performed with short periods of normothermic partial cardiopulmonary bypass and without cardioplegic arrest in most cases. In this study, we reviewed our experience with the extracardiac conduit Fontan operation, with a focus on early postoperative outcomes.
Between July 1992 and April 1997, 51 patients (median age 4.9 years) underwent an extracardiac conduit Fontan operation. Median cardiopulmonary bypass time was 92 minutes and has decreased significantly over the course of our experience. Intracardiac procedures were performed in only 5 patients (10%), and the aorta was crossclamped in only 11 (22%). Intraoperative fenestration was performed in 24 patients (47%). There were no early deaths. Fontan failure occurred in 1 patient who was a poor candidate for the Fontan procedure. Transient supraventricular tachyarrhythmias occurred in 5 patients (10%). Median duration of chest tube drainage was 8 days. Factors significantly associated with prolonged resource use (mechanical ventilation, inotropic support, intensive care unit stay, and hospital stay) included longer bypass time and higher Fontan pressure. At a median follow-up of 1.9 years, there was 1 death from bleeding at reoperation.
The extracardiac conduit Fontan procedure can be performed with minimal mortality and morbidity. Improved results may be related to advantages of the extracardiac approach and improved preservation of ventricular and pulmonary vascular function.
在Fontan手术的改良方法中,心外途径可能为优化术后早期心室和肺血管功能提供最大潜力,因为在大多数情况下,该手术可在短时间常温部分体外循环下进行,且无需心脏停搏。在本研究中,我们回顾了心外管道Fontan手术的经验,重点关注术后早期结果。
1992年7月至1997年4月期间,51例患者(中位年龄4.9岁)接受了心外管道Fontan手术。体外循环时间中位数为92分钟,在我们的经验过程中显著缩短。仅5例患者(10%)进行了心内操作,仅11例患者(22%)进行了主动脉阻断。24例患者(47%)术中进行了开窗术。无早期死亡病例。1例患者因不适合进行Fontan手术而出现Fontan失败。5例患者(10%)出现短暂性室上性心律失常。胸管引流时间中位数为8天。与资源使用时间延长(机械通气、血管活性药物支持、重症监护病房停留时间和住院时间)显著相关的因素包括体外循环时间延长和Fontan压力升高。中位随访1.9年时,1例患者在再次手术时因出血死亡。
心外管道Fontan手术可在死亡率和发病率极低的情况下进行。结果改善可能与心外途径的优势以及心室和肺血管功能的更好保存有关。