Gupta D, Rajwanshi A, Gupta S K, Nijhawan R, Saran R K, Singh R
Department of Cytology and Gynaecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Acta Cytol. 1999 Mar-Apr;43(2):191-4. doi: 10.1159/000330975.
To study the relationship between granulomas in the breast and tuberculous mastitis.
Retrospective analysis of 22 breast aspirates that showed epithelioid cell granulomas. The aspirates were reviewed and the cytomorphologic findings summarized.
Aspiration cytology revealed epithelioid cell granulomas along with giant cells, necrosis and inflammatory cell infiltrate. Overall acid-fast bacillus (AFB) positivity was 22.7%. AFB positivity was greater in the presence of necrosis when epithelioid cells were absent.
In a country like India, the diagnosis of granulomatous mastitis must be made with caution, even in the absence of AFB. Only after a sufficient trial of antituberculosis treatment has been given and the patient fails to respond should an alternative diagnosis be suggested.
研究乳腺肉芽肿与结核性乳腺炎之间的关系。
对22例显示上皮样细胞肉芽肿的乳腺抽吸物进行回顾性分析。对抽吸物进行复查并总结细胞形态学结果。
抽吸细胞学检查显示上皮样细胞肉芽肿伴有巨细胞、坏死和炎性细胞浸润。总体抗酸杆菌（AFB）阳性率为22.7%。当不存在上皮样细胞时，坏死情况下AFB阳性率更高。
在印度这样的国家，即使没有AFB，诊断肉芽肿性乳腺炎也必须谨慎。只有在给予充分的抗结核治疗试验且患者无反应后，才应提出其他诊断。
