Diallo R, Frevel T, Poremba C, Cirkel U, Metze D, Dockhorn-Dworniczak B
Gerhard-Domagk-Institut für Pathologie, Westfälische Wilhelms-Universität, Münster.
Pathologe. 1997 Jan;18(1):67-70. doi: 10.1007/s002920050198.
We report the rare case of granulomatous tuberculous mastitis based on lupus vulgaris in a 73-year-old female patient. The most important diagnostic procedure was the detection of mycobacterial DNA-sequences in paraffin-embedded tissues using the polymerase-chain-reaction (PCR). A combined antituberculous therapy lead to complete remission within 14 months after the diagnosis was established. The incidence of tuberculous mastitis among surgically treated lesions of the breast is less than 0.025 percent. Because of the frequent localisation of this disease in the upper outer quadrant of the breast and suspicious findings in mammography, tuberculous mastitis is one, even if rare, differential diagnosis for breast cancer.
我们报告了一例73岁女性患者中基于寻常狼疮的肉芽肿性结核性乳腺炎的罕见病例。最重要的诊断方法是使用聚合酶链反应(PCR)在石蜡包埋组织中检测分枝杆菌DNA序列。联合抗结核治疗在确诊后14个月内导致完全缓解。在接受手术治疗的乳腺病变中,结核性乳腺炎的发病率低于0.025%。由于这种疾病常位于乳腺的外上象限,且在乳房X光检查中有可疑发现,结核性乳腺炎是乳腺癌的一种鉴别诊断,即使很罕见。