Downey N J, McGuigan J A, Dolan S J, Russell C F
Department of Endocrine Surgery, Royal Victoria Hospital, Belfast, Northern Ireland.
Ir J Med Sci. 1999 Jan-Mar;168(1):13-6. doi: 10.1007/BF02939573.
Most mediastinal parathyroid tumours lie within the thymus gland and may be retrieved when cervical thymectomy is carried out in the course of neck exploration for primary hyperparathyroidism (HPT). We report 4 patients, each of whom required sternotomy for removal of a true mediastinal parathyroid adenoma. Subtraction isotope scintigraphy suggested the presence of a mediastinal tumour prior to cervical exploration in 2 individuals and prior to re-exploration in a third. When localisation before initial exploration for HPT suggests a parathyroid tumour within the chest, consideration should be given to proceeding to sternotomy, at first operation if a comprehensive neck exploration, including cervical thymectomy, fails to uncover the adenoma. Uniquely, one of our patients underwent sternotomy for HPT when 23 weeks pregnant.
大多数纵隔甲状旁腺肿瘤位于胸腺内,在因原发性甲状旁腺功能亢进症(HPT)进行颈部探查时行颈部胸腺切除术时可能会发现。我们报告4例患者,每例均需行胸骨切开术以切除真正的纵隔甲状旁腺腺瘤。减影同位素闪烁扫描显示,2例患者在颈部探查前、第3例患者在再次探查前存在纵隔肿瘤。如果在首次探查HPT之前进行的定位提示胸部有甲状旁腺肿瘤,若包括颈部胸腺切除术在内的全面颈部探查未能发现腺瘤,则在首次手术时应考虑行胸骨切开术。独特的是,我们的1例患者在怀孕23周时因HPT接受了胸骨切开术。