Hegarty N J, Fitzpatrick J M
Department of Surgery, 47 Eccles Street, Mater Misericordiae Hospital and University College Dublin, Dublin, Ireland.
Eur J Ultrasound. 1999 Mar;9(1):55-60. doi: 10.1016/s0929-8266(99)00012-9.
Benign prostatic hyperplasia (BPH) is an extremely common condition and represents a major health issue in terms of patient numbers and treatment cost. Traditionally, the choice of treatment has been between watchful waiting and surgery, however, the side effects of surgery lead to reluctance for treatment in many men, other than those with severe symptoms and complications. In the last 2 decades there has been a rapid expansion in the number of treatments being offered and the number of patients submitting to novel therapies. Medical management has evolved to achieve a central role in the management of BPH. Heat based treatments are also being investigated with considerable interest. Transrectal high intensity focused ultrasound (HIFU) is one such treatment, which allows radiation-free treatment, without the need for intra-urethral manipulation. Imaging can be performed during treatment and treatment results in symptomatic improvement, which is retained with medium-term follow-up. It involves a brief hospital stay and post-operative complications are few. The use of HIFU has also been extended to the treatment of renal, prostatic and bladder tumours and the results in these areas suggest further expansion of its role in urological practice.
良性前列腺增生(BPH)是一种极为常见的病症,就患者数量和治疗费用而言,是一个重大的健康问题。传统上,治疗选择一直是密切观察等待和手术,然而,手术的副作用导致许多男性,除了那些有严重症状和并发症的男性之外,不愿接受治疗。在过去20年里,所提供的治疗数量以及接受新疗法的患者数量都迅速增加。药物治疗已发展成为在BPH管理中发挥核心作用。基于热的治疗方法也受到了相当大的关注。经直肠高强度聚焦超声(HIFU)就是这样一种治疗方法,它允许无辐射治疗,无需进行尿道内操作。治疗期间可进行成像,治疗能改善症状,中期随访时症状改善情况得以维持。它住院时间短,术后并发症少。HIFU的应用也已扩展到肾、前列腺和膀胱肿瘤的治疗,这些领域的结果表明其在泌尿外科实践中的作用将进一步扩大。