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[外科患者的肠外营养]

[Parenteral feeding of surgical patients].

作者信息

Hartig W, Czarnetzki H D, Faust H, Fickweiler E

出版信息

Acta Chir Acad Sci Hung. 1978;19(1):75-86.

PMID:100997
Abstract
  1. Under stress an increased amount of labelled amino acids is incorporated. 2. Under the conditions of stress amino acids too participate in the process of synthesis. 15N-glycine was used as tracer in a quantity of 0.64 g of amino acid and 24 kcal per kg per day, that is at a 0.027 g per kcal. hour infusion rate, so that the infused 15N corresponded to 75% of the total residual nitrogen in healthy subjects and 57% in operated patients. 3. Sixteen percent of the infused 15N is secreted with the urine of healthy subjects as urine nitrogen, and 57% as urine nitrogen and 4--5% as ammonia nitrogen with the urine of the operated cases. 4. In contrast to normal conditions, under stress a higher percentage of the infused amino acids participates in energy production. 5. Stress enhances uropoiesis as in regards both quantity and speed. 6. No difference in acid-base balance was found in the case of postoperative infusion; urinary and plasma concentrations remained within normal limits.
摘要
  1. 在应激状态下,掺入的标记氨基酸量增加。2. 在应激条件下,氨基酸也参与合成过程。使用15N-甘氨酸作为示踪剂,用量为每千克每天0.64克氨基酸和24千卡,即每千卡每小时输注速率为0.027克,使得输注的15N相当于健康受试者总残余氮的75%,手术患者的57%。3. 输注的15N中有16%以尿氮形式随健康受试者的尿液排出,手术病例的尿液中57%以尿氮形式排出,4 - 5%以氨氮形式排出。4. 与正常情况相比,在应激状态下,输注的氨基酸有更高比例参与能量产生。5. 应激在数量和速度方面均增强尿生成。6. 术后输注时未发现酸碱平衡有差异;尿液和血浆浓度保持在正常范围内。

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