Wessels I F, Wessels D A, Zimmerman G J
Department of Ophthalmology, Chattanooga Unit, College of Medicine, University of Tennessee, USA.
Ophthalmic Surg Lasers. 1999 Mar;30(3):208-11.
Intravenous sedation to minimize discomfort from local anesthetic injection has many potential complications including severe involuntary sneezing (i.s.). This prospective study evaluates the occurrence of i.s. and a history of photic sneezing (p.s.).
All patients receiving local anesthesia (retrobulbar or periocular injections) after intravenous thiopentone for eye surgery during eight months were asked about p.s. and observed for i.s.
The 557 patients (40% males) had a mean age of 69.9 years and 14% recalled p.s. (29.5% males). I.s. developed in 5.2% of the 557. Only 7.6% of those with p.s. developed i.s. After periocular injections 23.8% developed as compared to 4.5% after retrobulbar injections. (P < 0.001). There was no relationship between p.s. and i.s. (p = 0.43).
I.s. is not linked to p.s., with males and females at equal risk for either. I.s. is more common after periocular injections.
静脉镇静以减轻局部麻醉注射带来的不适有许多潜在并发症,包括严重的不自主打喷嚏(i.s.)。这项前瞻性研究评估了i.s.的发生率以及光喷嚏反射(p.s.)病史。
在八个月期间,对所有在静脉注射硫喷妥钠后接受眼部手术局部麻醉(球后或眼周注射)的患者询问其p.s.情况,并观察i.s.情况。
557例患者(40%为男性)平均年龄69.9岁,14%回忆有p.s.(男性占29.5%)。557例中有5.2%发生i.s.。有p.s.的患者中只有7.6%发生i.s.。眼周注射后23.8%发生i.s.,而球后注射后为4.5%(P<0.001)。p.s.与i.s.之间无关联(p = 0.43)。
i.s.与p.s.无关,男性和女性发生这两种情况的风险相同。i.s.在眼周注射后更常见。