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A new method for dissolution studies of lipid-filled capsules employing nifedipine as a model drug.

作者信息

Pillay V, Fassihi R

机构信息

Temple University, School of Pharmacy, Department of Pharmaceutical Sciences, Philadelphia, Pennsylvania 19140, USA.

出版信息

Pharm Res. 1999 Feb;16(2):333-7. doi: 10.1023/a:1011959914706.

DOI:10.1023/a:1011959914706
PMID:10100323
Abstract
摘要

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1
A new method for dissolution studies of lipid-filled capsules employing nifedipine as a model drug.一种以硝苯地平为模型药物进行脂质填充胶囊溶出度研究的新方法。
Pharm Res. 1999 Feb;16(2):333-7. doi: 10.1023/a:1011959914706.
2
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In vitro dissolution studies on nifedipine capsules.硝苯地平胶囊的体外溶出度研究。
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Dissolution testing of soft shell capsules-acetaminophen and nifedipine.软胶囊（对乙酰氨基酚和硝苯地平）的溶出度测试
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Studies on dissolution tests for soft gelatin capsules. IV. Dissolution test of nifedipine soft gelatin capsule containing water soluble vehicles by the rotating dialysis cell method.软胶囊溶出度试验研究。IV. 采用旋转透析池法对含水溶性辅料的硝苯地平软胶囊进行溶出度试验。
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An in vitro-in vivo correlation study for nifedipine immediate release capsules administered with water, alcoholic and non-alcoholic beverages: Impact of in vitro dissolution media and hydrodynamics.硝苯地平速释胶囊与水、酒精饮料和非酒精饮料一起服用的体外-体内相关性研究：体外溶出介质和流体动力学的影响
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Int J Pharm. 2005 Aug 11;299(1-2):167-77. doi: 10.1016/j.ijpharm.2005.05.014.

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Challenges of Dissolution Methods Development for Soft Gelatin Capsules.

本文引用的文献

1
Evaluation and comparison of dissolution data derived from different modified release dosage forms: an alternative method.不同缓释剂型溶出数据的评估与比较：一种替代方法
J Control Release. 1998 Oct 30;55(1):45-55. doi: 10.1016/s0168-3659(98)00022-4.
2
Dissolution media for in vitro testing of water-insoluble drugs: effect of surfactant purity and electrolyte on in vitro dissolution of carbamazepine in aqueous solutions of sodium lauryl sulfate.水不溶性药物体外测试的溶出介质：表面活性剂纯度和电解质对卡马西平在十二烷基硫酸钠水溶液中体外溶出的影响
J Pharm Sci. 1997 Mar;86(3):384-8. doi: 10.1021/js960105t.
3
Establishment of sink conditions in dissolution rate determinations. Theoretical considerations and application to nondisintegrating dosage forms.
软胶囊溶出方法开发的挑战
Pharmaceutics. 2021 Feb 4;13(2):214. doi: 10.3390/pharmaceutics13020214.
4
Mechanistic analysis of solute transport in an in vitro physiological two-phase dissolution apparatus.体外生理双相溶解装置中溶质传递的机理分析。
Biopharm Drug Dispos. 2012 Oct;33(7):378-402. doi: 10.1002/bdd.1803. Epub 2012 Sep 4.
5
In vitro gastrointestinal lipolysis of four formulations of piroxicam and cinnarizine with the self emulsifying excipients Labrasol and Gelucire 44/14.四种含有自乳化辅料Labrasol和Gelucire 44/14的吡罗昔康和桂利嗪制剂的体外胃肠道脂解作用
Pharm Res. 2009 Aug;26(8):1901-10. doi: 10.1007/s11095-009-9906-2. Epub 2009 May 19.
6
Application of powder rheometer to determine powder flow properties and lubrication efficiency of pharmaceutical particulate systems.应用粉末流变仪测定药物颗粒系统的粉末流动性质和润滑效率。
AAPS PharmSciTech. 2005 Oct 19;6(3):E398-404. doi: 10.1208/pt060349.
溶出速率测定中漏槽条件的建立。理论考量及在非崩解剂型中的应用。
J Pharm Sci. 1967 Oct;56(10):1238-42. doi: 10.1002/jps.2600561005.
4
Effect of vehicle amphiphilicity on the dissolution and bioavailability of a poorly water-soluble drug from solid dispersions.
J Pharm Sci. 1988 May;77(5):414-7. doi: 10.1002/jps.2600770512.
5
Bioavailability of a poorly water-soluble drug from tablet and solid dispersion in humans.
J Pharm Sci. 1991 Jul;80(7):712-4. doi: 10.1002/jps.2600800722.