Majumdar S
Magnetic Resonance Science Center, Department of Radiology, University of California, San Francisco 94143, USA.
Technol Health Care. 1998 Dec;6(5-6):321-7.
Bone mineral density and three-dimensional trabecular structure play a significant role in predicting bone strength and biomechanical properties. MR is a non-invasive technique for determining trabecular architecture both in vivo and in vitro. In this paper we review the use of magnetic resonance imaging to obtain high resolution images of trabecular bone structure and quantify the three-dimensional architecture of the trabecular bone network. Studies assessing the anisotropy of the trabecular architecture in human cadaveric specimens from the distal and proximal femur, and the thoracic and lumbar vertebrae, are reviewed. The contributions of the MR derived measures of 3D trabecular bone structure to the biomechanical strength of the specimen are presented. In vivo, the relationship between the high resolution MR derived trabecular bone structure parameters in the distal radius and calcaneus in patients with hip fractures, are compared to age matched normal controls. MR derived measures are compared to measures of trabecular bone mineral density (BMD) in the hip using dual X-ray absorptiometry (DXA).
骨密度和三维小梁结构在预测骨强度和生物力学特性方面发挥着重要作用。磁共振成像（MR）是一种用于在体内和体外确定小梁结构的非侵入性技术。在本文中，我们回顾了利用磁共振成像来获取小梁骨结构的高分辨率图像，并对小梁骨网络的三维结构进行量化。文中还综述了评估来自股骨远端和近端以及胸椎和腰椎的人体尸体标本中小梁结构各向异性的研究。介绍了磁共振成像得出的三维小梁骨结构测量值对标本生物力学强度的贡献。在体内，将髋部骨折患者桡骨远端和跟骨中通过高分辨率磁共振成像得出的小梁骨结构参数与年龄匹配的正常对照进行比较。将磁共振成像得出的测量值与使用双能X线吸收法（DXA）测量的髋部小梁骨密度（BMD）进行比较。
