Lorenc R S
Zakładu Biochemii i Medycyny Doświadczalnej Instytutu Pomnik-Centrum Zdrowia Dziecka.
Pol Merkur Lekarski. 1998 Oct;5(28):236-7.
Calcitonin is one of three most important factors involved in the regulation of systemic calcium homeostasis. Since its discovery in 1961 the structure of calcitonin from different species including human was established, synthetized and developed for use in human clinic. Up to now calcitonin is utilized in treatment of hypercalcemia, Paget disease, algodystrophy, primary and secondary osteoporosis and analgesia. Beside comparative studies aiming on selection of the most effective protocol of treatment and utilization, lately calcitonin is extensively studies for its antifracture potency in osteoporosis. One of the substantial therapeutical progress also appeared the utilization of intransal preparation of calcitonin.
降钙素是参与全身钙稳态调节的三个最重要因素之一。自1961年被发现以来，包括人类在内的不同物种的降钙素结构得以确立、合成并开发用于人类临床。到目前为止，降钙素被用于治疗高钙血症、佩吉特病、痛性营养不良、原发性和继发性骨质疏松症以及止痛。除了旨在选择最有效治疗方案和用途的比较研究外，最近降钙素因其在骨质疏松症中的抗骨折效力而受到广泛研究。降钙素鼻内制剂的应用也出现了一项重大治疗进展。
