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儿童幽门螺杆菌胃炎:克拉霉素、阿莫西林和奥美拉唑2周治疗的疗效

Helicobacter pylori gastritis in children: efficacy of 2 weeks of treatment with clarithromycin, amoxicillin and omeprazole.

作者信息

Tirén U, Sandstedt B, Finkel Y

机构信息

Department of Women and Child Health, Karolinska Institutet, St. Görans' Children's Hospital, Stockholm, Sweden.

出版信息

Acta Paediatr. 1999 Feb;88(2):166-8. doi: 10.1080/08035259950170330.

Abstract

Thirty-eight children with Helicobacter pylori gastritis diagnosed by histopathology, and/or bacteriological culture were treated with omeprazole, amoxicillin and clarithromycin. Follow-up endoscopy was performed in 34 children. Outcome was measured by negative histology and culture for H. pylori. Six patients were excluded. Of the 32 remaining children eradication was achieved in 75% (95% confidence interval 60-90%).

摘要

38名经组织病理学和/或细菌学培养确诊为幽门螺杆菌胃炎的儿童接受了奥美拉唑、阿莫西林和克拉霉素治疗。34名儿童接受了随访内镜检查。治疗结果通过幽门螺杆菌组织学和培养阴性来衡量。6名患者被排除。在其余32名儿童中,75%(95%置信区间60 - 90%)实现了根除。

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