Mehrotra P K
Indian J Physiol Pharmacol. 1976 Oct-Dec;20(4):235-8.
Effect of two different dose ratios of estrogen (E) and progesterone (P) (1:1000; 1:10,000) on the morphological and biochemical response of the uterus, cervix and the vagina of ovariectomized estrogen pretreated rats was studied. It was observed that the dose ratio of E & P at 1:1000 did not produce any remarkable ponderal and histological changes from that seen under the influence of estrogen alone. Whereas, in the dose ratio of E & P at 1:10,000 progesterone appeared to inhibit the effect of estrogen. The biochemical response of the uterus, cervix and vagina, however, varied from each other in both the dose ratios.
研究了两种不同雌激素（E）与孕激素（P）剂量比（1:1000；1:10000）对卵巢切除且经雌激素预处理大鼠子宫、宫颈和阴道形态及生化反应的影响。观察到，E与P剂量比为1:1000时，与单独使用雌激素相比，未产生任何显著的重量和组织学变化。然而，E与P剂量比为1:10000时，孕激素似乎抑制了雌激素的作用。不过，两种剂量比下子宫、宫颈和阴道的生化反应各不相同。
