Gordon T, Sorlie P, Kannel W B
Int J Epidemiol. 1976 Dec;5(4):327-34. doi: 10.1093/ije/5.4.327.
The reliability of casual blood pressures for reflecting blood pressure status and predicting cardiovascular sequelae of hypertension was examined in the Framingham cohort of 5209 men and women followed for 18 years. Blood pressures were more variable in persons with higher levels. After controlling for pressure level the degree of variability in an individual at one point in time did not correlate with the degree of varability at another time. Although a single casual measurement does not afford a precise characterization for an individual it was found to be highly predictive of future cardiovascular disease. A series of blood pressure measurements (averaged) improved the predictability somewhat but this seemed to be fully explicable by the greater stability of an average of several measurements as against a single measurement.
在弗雷明汉队列研究中，对5209名男性和女性进行了18年的随访，以检验随机血压反映血压状况及预测高血压心血管后遗症的可靠性。血压水平较高者的血压变异性更大。在控制血压水平后，个体在某一时刻的变异性程度与另一时刻的变异性程度并无关联。尽管单次随机测量无法为个体提供精确的特征描述，但发现其对未来心血管疾病具有高度预测性。一系列血压测量值（取平均值）在一定程度上提高了预测能力，但这似乎完全可以通过多次测量平均值比单次测量更稳定来解释。
