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1956年布拉干萨保利斯塔县的类天花:疫情及其研究的总体描述

Variola minor in Bragança Paulista County, 1956: overall description of the epidemic and of its study.

作者信息

Angulo J J

出版信息

Int J Epidemiol. 1976 Dec;5(4):359-66. doi: 10.1093/ije/5.4.359.

Abstract

An overall description of the epidemic of variola minor (alastrim) affecting Bragança Paulista County (Brazil) in 1956 is given. A total of 484 cases were recorded for 210 households, one hotel and one boarding school. At least 95 per cent of the households with cases of the disease in the capital city were surveyed and 90 per cent of the households in the rural districts. An orphanage, an old folk's home, the County jail and 10 schools operating in the capital city and some other social groups without cases were also surveyed, as well as 125 households without cases but with one or more contacts with the disease. An overall attack rate of 1924 cases, 267 cases and 781 cases per 100,000 inhabitants was obtained, respectively, for the capital city, the rural environment and the whole County. Clinical, epidemiological, serological and environmental surveys were conducted. Evidence on identification of the epidemic disease is presented. Study of the epidemic was made at these levels: the disease itself (frequency and severity); the disease in the individual (association of characteristics of persons with occurrence and clinical severity of variola minor); the disease in social units (occurrence and spread in households and school classes); the disease in small communities (occurrence and spread in housing projects, city blocks and farms); the disease in two large communities with contrasting socio-economic characteristics (the capital city and the rural environment); and the disease in the County as a whole.

摘要

本文给出了1956年发生在巴西布拉干萨保利斯塔县的轻型天花(类天花)疫情的总体描述。共记录了210户家庭、1家酒店和1所寄宿学校的484例病例。对首府城市至少95%有病例的家庭以及农村地区90%的家庭进行了调查。还对一家孤儿院、一家养老院、县监狱以及首府城市运营的10所学校和其他一些无病例的社会群体进行了调查,以及125户无病例但有一个或多个与该病接触者的家庭。首府城市、农村地区和全县每10万居民的总发病率分别为19[此处原文可能有误,推测应为1924]例、267例和781例。进行了临床、流行病学、血清学和环境调查。提供了关于确诊该流行病的证据。从以下几个层面开展了对该疫情的研究:疾病本身(发病率和严重程度);个体层面的疾病(个体特征与轻型天花发病及临床严重程度的关联);社会单位层面的疾病(家庭和班级中的发病及传播情况);小社区层面的疾病(住房项目、街区和农场中的发病及传播情况);具有不同社会经济特征的两个大社区层面的疾病(首府城市和农村地区);以及全县层面的疾病。

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