Paul E
Hautarzt. 1976 Dec;27(12):599-602.
A lentigo maligna melanoma on the glans penis and the orificium urethrae is described. From the clinical point of view a superficial spreading melanoma as well as a lentigo maligna could be considered as differential diagnoses. The flat part of this lesion, however, was a lentigo maligna when investigated using a lightmicroscope and especially fluorescence-microscope. In the lightmicroscope only single heavily pigmented and dendritically branched cells could be seen in the basal parts of the epidermis. The definite shape of the other tumor cells was not identifiable. With the fluorescence microscope, however, in nearly all fluorescing and atypical pigment cells, dendritic branching clearly was present.
本文描述了一例发生于阴茎头和尿道外口的恶性雀斑样痣黑色素瘤。从临床角度来看，浅表扩散性黑色素瘤以及恶性雀斑样痣都可作为鉴别诊断。然而，当使用光学显微镜尤其是荧光显微镜进行检查时，该病变的扁平部分为恶性雀斑样痣。在光学显微镜下，仅在表皮基部可见单个色素沉着严重且呈树枝状分支的细胞。其他肿瘤细胞的明确形态无法辨认。然而，使用荧光显微镜时，几乎所有发荧光的非典型色素细胞均明显呈现树枝状分支。
