Pierquin B, Baillet F, Mueller W, Wilson F
J Radiol Electrol Med Nucl. 1976 Nov;57(11):841-3.
The current status of knowledge regarding low rate telecobalt irradiation does not permit any definitive conclusions. However, it has shown that this technique of irradiation, on condition that it is given in two fractions separated by three weeks, is without major risk for healthy tissue, the tolerance of skin being particularly remarkable, and with immediate very satisfactory results on the tumour. Strict statistical comparison will be necessary, however, if a final judgment is to be made. Thus a study group of the O.E.R.T.C. has decided to undertake a comparative study between classical fractioned irradiation and semi-continuous low rate irradiation. The trial involves only cancers of the base of the tongue he has began in January 1976.
关于低剂量率远距离钴照射的现有知识状况尚无法得出任何明确结论。然而,已经表明,这种照射技术,只要分两次给予,间隔三周,对健康组织没有重大风险,皮肤耐受性尤其显著,并且对肿瘤能立即产生非常令人满意的效果。然而,如果要做出最终判断,严格的统计学比较将是必要的。因此,欧洲肿瘤研究与治疗组织(O.E.R.T.C.)的一个研究小组决定对经典分次照射和半连续低剂量率照射进行一项比较研究。该试验仅涉及舌根癌,已于1976年1月开始。