Castera D, Legros M, Mouillet J
J Radiol Electrol Med Nucl. 1978 Nov;59(11):611-4.
A new method of irradiation known as hyperfractionated radiotherapy was studied in 56 patients with cancers in the region of the ear, nose, and throat. The dose was 72 grays given during 80 sessions over a period of 28 days, with a rest period of two weeks at the half-way point. Each session lasted 2 hours. The results (complications and survival rate) were compared with those obtained in a control group treated with 70 grays in 35 sessions over a period of 7 weeks. The complication rate was 21% in the series treated with hyperfractionated radiotherapy, against 19% in those given classical treatment (results not significant). The survival rate was better, however, (63% against 33% after 18 months), for the patients treated with this new method of irradiation.
一种被称为超分割放射疗法的新放疗方法在56例耳鼻喉部位癌症患者中进行了研究。剂量为72戈瑞,在28天内分80次给予,在疗程进行到一半时休息两周。每次治疗持续2小时。将结果(并发症和生存率)与在7周内分35次给予70戈瑞治疗的对照组结果进行比较。超分割放射治疗组的并发症发生率为21%,传统治疗组为19%(结果无显著差异)。然而,采用这种新放疗方法治疗的患者生存率更高(18个月后分别为63%和33%)。