Iivanainen M, Arho P
J Ment Defic Res. 1976 Dec;20(4):285-8. doi: 10.1111/j.1365-2788.1976.tb00955.x.
To study the distribution of the skin involvement in the cutis verticis gyrata and mental retardation (CVG-MR) syndrome skin thickness was determined radiographically on the flexor aspect of the forearm of ten patients with this syndrome. The skin of patients was thicker than that of normal controls but the difference was quite significant (1.4 +/- 0.4 mm versus 1.1 +/- 0.2 mm; p less than 0.05). When the analysis was applied to males only, the difference was statistically significant (1.5 +/- 0.3 versus 1.1 +/- 0.2 mm; p less than 0.01). There was no difference in skin thickness between the primary and miscellaneous forms of the syndrome. The findings suggest generalised skin involvement in the CVG-MR syndrome.
为研究皮肤回旋状颅皮症伴智力发育迟缓（CVG-MR）综合征中皮肤受累情况，对10例该综合征患者前臂屈侧进行X线摄片测定皮肤厚度。患者的皮肤比正常对照者厚，但差异非常显著（1.4±0.4毫米对1.1±0.2毫米；p＜0.05）。仅对男性进行分析时，差异具有统计学意义（1.5±0.3对1.1±0.2毫米；p＜0.01）。该综合征的原发性和混合型在皮肤厚度上无差异。这些发现提示CVG-MR综合征存在全身性皮肤受累。
