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小脑植入物中电极配置的评估。

Evaluation of electrode configurations in cerebellar implants.

作者信息

Sances A, Larson S J, Myklebust J, Swiontek T, Millar E A, Cusick J F, Hemmy D C, Jodat R, Ackmann J

出版信息

Appl Neurophysiol. 1977;40(2-4):141-59. doi: 10.1159/000102451.

Abstract

Capacitively coupled currents of 100 Hz, 0.25 msec duration, were applied to multielectrode arrays implanted upon the superior and posterior surfaces of the chimpanzee cerebellum. The current required for 90% reduction in the amplitude of the evoked potential was inversely proportional to the number of electrodes upon the cerebellar surface. A study of various waveforms showed that z Hz, 0.25 msec pulse duration is near optimal for reduction of amplitude of the somatosensory evoked potential. The current densities per electrode were 5--11 mA/cm2 with a charge per pulse of 0.04--0.08 muC in humans with 15--20 electrodes on each superior surface and 10 electrodes on each posterior cerebellar surface.

摘要

将持续时间为0.25毫秒、频率为100赫兹的电容耦合电流施加到植入黑猩猩小脑上表面和后表面的多电极阵列上。诱发电位幅度降低90%所需的电流与小脑表面电极数量成反比。对各种波形的研究表明,频率为z赫兹、脉冲持续时间为0.25毫秒的电流在降低体感诱发电位幅度方面接近最佳。在人类中,每个上表面有15至20个电极,每个小脑后表面有10个电极,每个电极的电流密度为5-11毫安/平方厘米,每个脉冲的电荷量为0.04-0.08微库仑。

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