Pasternac A, Noble J, Streulens Y, Lespérance J, Bourassa M G
Arch Mal Coeur Vaiss. 1978 Aug;71(8):878-86.
The authors have compared myocardial perfusion, i.e. the coronary blood flow per unit of myocardial mass, in 9 patients with cardiomyopathy and 5 normal subjects, both at rest and during coronary sinus pacing-induced tachycardia at a rate of 150 beats/mn. In the cardiomyopathies, myocardial perfusion was found to be decreased at rest, and to remain abnormally low during induced tachycardia despite the evidence for a significant coronary reserve. During pacing there were, in addition to induced chest pain, indirect signs of sub-endocardial ischaemia which could explain the angina of effort found in certain cardiomyopathies, especially those of the obstructive hypertrophic type.
作者比较了9例心肌病患者和5名正常受试者在静息状态以及冠状窦起搏诱发的150次/分钟心动过速期间的心肌灌注情况,即单位心肌质量的冠状动脉血流量。在心肌病患者中,发现静息时心肌灌注降低,并且在诱发心动过速期间尽管有明显的冠状动脉储备,但心肌灌注仍异常低下。起搏期间,除了诱发胸痛外,还有心内膜下缺血的间接征象,这可以解释某些心肌病,尤其是梗阻性肥厚型心肌病中出现的劳力性心绞痛。