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[刺激强度对猫皮质额叶区神经元反应的影响]

[Effect of stimulus intensity on neuronal reactions of the frontal region of the cat cortex].

作者信息

Dem'ianenko V S

出版信息

Neirofiziologiia. 1976;8(6):606-12.

PMID:1012400
Abstract

The pulse activity of neurons of the cortex frontal region was studied in cat under conditions of acute experiment under chloralose (70 mg/kg) by means of extracellular recording. The stimulus intensity varied in the near threshold range (15-16 db over the threshold of a summarized evoked potentional). A comparative analysis of the neuronal responses of specific (field S1) and nonspecific projections demonstrated similar in principle reconstructions with an increase in the stimulus intensity: a decrease in the latent period, rise in total frequency and phase of the discharge, an increase in the response probability. However, a relatively stable level of the latent period and the response probability were achieved for neurons of specific projection at the stimulus intensity equal 3-5 of threshold units, and for neurons of nonspecific projections at the stimulus intensity equal to 10-15 of threshold units. All sensory projections in the frontal cortex are formed by two inputs: short-latent low-threshold and long-latent high-threshold. Analysis of modal conditioned differences in threshold sensitivity and duration of the latent period of the polysensory neurons responses gives reason to assume the convergence of different modal signals right on cortical neurons.

摘要

在氯醛糖(70毫克/千克)麻醉下,通过细胞外记录法在急性实验条件下研究了猫额叶皮质神经元的脉冲活动。刺激强度在接近阈值的范围内变化(比总和诱发电位阈值高15 - 16分贝)。对特异性(体感区S1)和非特异性投射的神经元反应进行的比较分析表明,随着刺激强度的增加,原则上重建相似:潜伏期缩短、放电总频率和相位增加、反应概率增加。然而,对于特异性投射的神经元,在刺激强度等于阈值单位的3 - 5倍时,潜伏期和反应概率达到相对稳定的水平;对于非特异性投射的神经元,在刺激强度等于阈值单位的10 - 15倍时达到相对稳定的水平。额叶皮质中的所有感觉投射由两种输入形成:短潜伏期低阈值和长潜伏期高阈值。对多感觉神经元反应的阈值敏感性和潜伏期持续时间的模态条件差异分析,有理由假设不同模态信号在皮质神经元上直接汇聚。

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