Kolygin B A, Vesnin A G
Pediatr Radiol. 1976 Dec 15;5(2):75-80. doi: 10.1007/BF00975311.
In 160 children with Hodgkin's disease, lung involvement was studied. In 14.4%, lung lesions were diagnosed at the first admission and an additional 7.5% of the patients developed lung lesions in the course of the disease. As a rule lung involvement was observed in advanced disease. It has been stated that there is no particular difference in the response to treatment in any particular type of lesion, spread either by contiguity of dissemination. Of all methods of treatment, combination chemotherapy (MOPP programme) showed the best results. In our series of children it was not possible to show any advantage to favour irradiation as against combination chemotherapy in the treatment of lung lesions.
对160例霍奇金病患儿的肺部受累情况进行了研究。14.4%的患儿在首次入院时被诊断有肺部病变,另有7.5%的患儿在病程中出现肺部病变。通常在疾病晚期观察到肺部受累。据称,对于任何特定类型的病变,无论是通过连续性扩散还是播散性扩散,其对治疗的反应没有特别差异。在所有治疗方法中,联合化疗(MOPP方案)显示出最佳效果。在我们的儿童系列病例中,在肺部病变的治疗中,无法显示出放疗相对于联合化疗有任何优势。