Vercelli-Retta J, Silveira R, Dajas F, Rodríguez D
Acta Anat (Basel). 1976;96(4):534-46. doi: 10.1159/000144710.
The interfascicular oligodendroglia of the rat striatum nucleus is studied in control animals and under experimentally induced brain edemas. Enzyme histochemical studies were performed. Normal oligodendrocytes show two different enzymatic distributions. While Mg2+-ATPase, TPPase, TPPase, adenylate cyclase and SDH are shown to be situated at the cell bodies and some proximal processes, 5'-nucleotidase reaction is seen at the cell fine distal processes. In spite of its trong activity in oligodendroglial endings the latter enzyme is not seen at the myelin sheath. This sheath and the interfascicular cells being intimately related, 5'-nucleotidase appears to be important not only during myelination, as almost all authors emphasize, but also in the adult myelin metabolism. Experimental brain edema shows some changes in the interfasicular oligodendroglia enzymatic activites for 5'-nucleotidase, Mg2+-ATPase and adenylate cyclase. A progressive disappearance of the former enzyme is observed. These features and those of derived from local ionic alterations may be concerned with the special susceptibility of white matter for some types of brain swellings.
对正常动物以及实验性诱导脑肿胀情况下大鼠纹状体核的束间少突胶质细胞进行了研究。开展了酶组织化学研究。正常少突胶质细胞呈现出两种不同的酶分布情况。镁离子 - 三磷酸腺苷酶（Mg2+-ATPase）、硫胺素焦磷酸酶（TPPase）、腺苷酸环化酶和琥珀酸脱氢酶（SDH）位于细胞体和一些近端突起处，而5'-核苷酸酶反应则见于细胞的细小远端突起处。尽管该酶在少突胶质细胞终末具有很强的活性，但在髓鞘上却未见其存在。髓鞘与束间细胞密切相关，5'-核苷酸酶似乎不仅在髓鞘形成过程中很重要，正如几乎所有作者所强调的那样，而且在成年期的髓鞘代谢中也很重要。实验性脑肿胀显示束间少突胶质细胞的5'-核苷酸酶、Mg2+-ATPase和腺苷酸环化酶的酶活性出现了一些变化。观察到前一种酶逐渐消失。这些特征以及源自局部离子改变的特征可能与白质对某些类型脑肿胀的特殊易感性有关。
