Grzybowski S, Galbraith J D, Dorken E
Tubercle. 1976 Dec;57(4):263-9.
One hundred and two cases of inactive tuberculosis, 165 positive tuberculin reactors and 103 previous BCG vaccinated individuals showing large tuberculin reactions were placed on the completely supervised regimen consisting of isoniazid and ethambutol given three times a week. Over 90% of these individuals completed 18 months' treatment. There were no active cases of tuberculosis among the treated groups during the observation period averaging 34.8 months. The control groups consisting of 217 individuals had 9 cases of active tuberculosis giving an annual risk of developing the disease of 1.8 per 1000.
102例非活动性肺结核患者、165例结核菌素反应阳性者以及103例曾接种卡介苗且结核菌素反应呈强阳性者，接受了由异烟肼和乙胺丁醇组成的完全督导治疗方案，每周给药3次。这些患者中超过90%完成了18个月的治疗。在平均为期34.8个月的观察期内，治疗组未出现活动性肺结核病例。由217人组成的对照组中有9例活动性肺结核病例，疾病年发病风险为每1000人中有1.8例。
