Gracheva Z A, Babakova S V, Gorodilova V V, Sokolova I I
Vopr Onkol. 1976;22(10):19-21.
One of the methods reflecting the state of antitumor cell immunity is skin allergic reaction of delayed hypersensitivity to injection of antitumor antigen, which together with other indices is believed to be of certain importance in estimating the immune response of the cancer patient organism. The authors compared quantitative and morphological changes in blood basophilic granulocytes and the data of skin allergic reaction. The results of studies conducted indicated that changes in the quantity and degranulation of basophilic leucocytes may be used along with skin allergic response of delayed hypersensitivity as one of the criteria for estimation of the degree of sensibilization of the organism of gastric cancer patients.
反映抗肿瘤细胞免疫状态的方法之一是对注射抗肿瘤抗原产生的迟发型超敏皮肤过敏反应,人们认为该反应与其他指标一起在评估癌症患者机体的免疫反应方面具有一定重要性。作者比较了血液嗜碱性粒细胞的数量和形态变化以及皮肤过敏反应的数据。所进行的研究结果表明,嗜碱性白细胞数量和脱颗粒的变化可与迟发型超敏皮肤过敏反应一起用作评估胃癌患者机体致敏程度的标准之一。