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[肿瘤抗原对胃癌患者血液中白细胞黏附的影响]

[Effect of tumor antigens on leukocyte adherence in the blood in stomach cancer].

作者信息

Zharkov V V, Novikov D K

出版信息

Vopr Onkol. 1983;29(2):14-8.

PMID:6836968
Abstract

The reaction of changes in leukocyte adherence was compared in 79 cases of stomach cancer, 44 cases of other gastric diseases and healthy subjects. Tumor antigens were shown to inhibit the adherence of lymphocytes and granulocytes in 61 out of 79 cancer patients (77,2%); adherence inhibition was more frequently observed in patients with stage I-III tumors than in cases of stage IV tumors. The removal of the antigens of normal mucosa from tumor tissue extracts did not affect the frequency of positive reactions in cancer patients significantly. However, the frequency dropped from 22-34 to 2.3-13.6% in the group of non-tumor patients.

摘要

对79例胃癌患者、44例其他胃部疾病患者和健康受试者的白细胞黏附变化反应进行了比较。结果显示,79例癌症患者中有61例(77.2%)的肿瘤抗原可抑制淋巴细胞和粒细胞的黏附;I - III期肿瘤患者比IV期肿瘤患者更常出现黏附抑制现象。从肿瘤组织提取物中去除正常黏膜抗原,对癌症患者阳性反应的频率没有显著影响。然而,在非肿瘤患者组中,该频率从22 - 34%降至2.3 - 13.6%。

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