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[人脑胶质瘤组织中的糖原分解]

[Glycogen breakdown in the tissue of human cerebral glial tumors].

作者信息

Akopian A S, Popova I A, Promyslov M Sh, Rozenfel'd E L

出版信息

Vopr Neirokhir. 1976 Nov-Dec(6):38-41.

PMID:1014528
Abstract

The activity of gamma-amylase (acid alpha-glucosidase) and phosphorylase in the tissue of human glial tumours and the brain tissue adjacent to the tumour was studied. A sharp (more than three-fold) increase of the activity of gamma-amylase was found in the tissue of glial tumours. In the adjacent tissues of the brain its activity was also elevated (approximately, two-fold). The activity of phosphorylase is practically lacking in human glial tumours, and is only slightly apparent in the brain tissue neighbouring the tumour. Gamma-amylase may be suggested to play an important role in glycogen metabolism of glial tumours in man.

摘要

对人类胶质细胞瘤组织及肿瘤邻近脑组织中γ-淀粉酶(酸性α-葡萄糖苷酶)和磷酸化酶的活性进行了研究。结果发现,胶质细胞瘤组织中γ-淀粉酶的活性急剧增加(超过三倍)。在脑的邻近组织中其活性也有所升高(约两倍)。人类胶质细胞瘤中几乎不存在磷酸化酶的活性,仅在肿瘤邻近的脑组织中略有显现。可以认为γ-淀粉酶在人类胶质细胞瘤的糖原代谢中起重要作用。

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