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膝关节肿瘤切除关节融合术:大型间置同种异体骨及长髓内钉技术

Resection arthrodesis of the knee for tumor: large intercalary allograft and long intramedullary nail technique.

作者信息

Benevenia J, Makley J T, Locke M, Gentili A, Heiner J

机构信息

Department of Orthopaedic Surgery, Case Western Reserve University School of Medicine and Musculoskeletal Tumor Center, University Hospitals of Cleveland, OH.

出版信息

Semin Arthroplasty. 1994 Apr;5(2):76-84.

Abstract

Twenty-five patients had a procedure consisting of resection of the distal femur or proximal tibia for aggressive or malignant neoplasms. The resulting bony gap was bridged by allografts averaging 18 cm in length. Fixation was achieved using a long fluted intramedullary nail. The average follow-up time and time to union were 3 years (range, 0.25 to 9 years) and 13 months (range, 6 to 28 months), respectively. Eleven patients had nononcologic complications related to the index surgical procedure, including two patients with allograft nonunion. There were no infections. Three patients had amputations for local recurrence of their tumor. Twenty patients (80%) had no evidence of tumor at the time of follow-up. According to the Evaluation System of the Musculoskeletal Tumor Society, 80% of patients had a satisfactory result. No patient had a nononcologic complication resulting in total failure or amputation. The procedure of resection-arthrodesis of the knee using a large allograft with a long intramedullary nail provides patients with a stable, durable biological reconstruction that allows early weight-bearing, and the procedure carries a low incidence of infection.

摘要

25例患者接受了因侵袭性或恶性肿瘤而行的股骨远端或胫骨近端切除术。所形成的骨缺损采用平均长度为18 cm的同种异体骨进行桥接。使用长槽髓内钉进行固定。平均随访时间和骨愈合时间分别为3年(范围0.25至9年)和13个月(范围6至28个月)。11例患者出现与初次手术相关的非肿瘤性并发症,包括2例同种异体骨不愈合患者。无感染发生。3例患者因肿瘤局部复发而接受截肢。20例患者(80%)在随访时无肿瘤证据。根据肌肉骨骼肿瘤学会评估系统,80%的患者结果满意。无患者因非肿瘤性并发症导致完全失败或截肢。采用大型同种异体骨和长髓内钉进行膝关节切除关节固定术,为患者提供了一种稳定、持久的生物学重建方法,可允许早期负重,且该手术感染发生率低。

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