Krailadsiri P, Seghatchian J
Department of Laboratory Medicine, Chulalongkorn University Hospital, Bangkok, Thailand.
Transfus Sci. 1994 Jun;15(2):179-83. doi: 10.1016/0955-3886(94)90093-0.
We describe a new approach for assessing filtration-induced changes in cellular indices of platelet concentrates at the beginning and the end of storage, using pairs of identical packs. The results revealed that post-filtered products did not store as well as their counterparts. Filtration did not induce any significant changes on aggregation as determined by spontaneous aggregation nor was there a disparity between leucocyte peroxidase/basophil count. We recommend filtration on day 2 which causes minimal loss of platelets and less change in the mean platelet volume.
我们描述了一种新方法，通过使用成对的相同包装来评估储存开始和结束时血小板浓缩物细胞指标的过滤诱导变化。结果显示，过滤后的产品储存效果不如未过滤的对照产品。通过自发聚集测定，过滤未引起聚集的任何显著变化，白细胞过氧化物酶/嗜碱性粒细胞计数也没有差异。我们建议在第2天进行过滤，这样血小板损失最小，平均血小板体积变化也较小。
