Horak D, Svec F, Adamyan A, Titova M, Voronkova O, Trostenyuk N, Vishnevskii V, Guseinov E, Gumargalieva K
Institute of Macromolecular Chemistry, Czechoslovak Academy of Sciences, Prague, Czechoslovakia.
Clin Mater. 1990;6(4):287-97. doi: 10.1016/0267-6605(90)90049-2.
Spherical particles of porous poly(2-hydroxyethyl methacrylate) have been used in the treatment of patients suffering from focal alterations of the liver, namely haemangioma and hypervascular tumour. The treatment consisted of the preoperative endovascular occlusion of branches of the hepatic artery using these spherical particles, and was followed by an operation. The main merit of the preoperative occlusion of blood vessels is that it substantially reduces blood loss during surgery. In order to determine the optimal time for the operation on the liver, indicators of the coagulation system were examined in successive terms of the postemboilization period. Reaction of the organism to endovascular occlusion is reflected in hypercoagulation changes in the coagulation system.
多孔聚甲基丙烯酸2-羟乙酯球形颗粒已用于治疗患有肝脏局灶性病变的患者，即肝血管瘤和高血运肿瘤。治疗方法包括术前使用这些球形颗粒对肝动脉分支进行血管内栓塞，然后进行手术。术前血管栓塞的主要优点是它能显著减少手术中的失血量。为了确定肝脏手术的最佳时间，在栓塞术后的连续时间段内检查了凝血系统指标。机体对血管内栓塞的反应表现为凝血系统的高凝变化。
