Schönberger J P, Everts P A, Bredee J J, Jansen E, Goedkoop R, Bavinck J H, Berreklouw E, Wildevuur C R
Department of Cardiopulmonary Surgery, Catharina Hospital, Eindhoven, The Netherlands.
Perfusion. 1992;7(4):257-62. doi: 10.1177/026765919200700403.
The efficacy of two blood conservation techniques in decreasing and in preventing the use of homologous blood products was retrospectively studied in 150 patients undergoing internal mammary artery bypass surgery. Patients were matched according to prebypass blood haemoglobin (Hb) content and body surface area and were allocated to one of three groups: in the patients of group 1 (n = 50), normovolaemic anaemia (NA) was accepted postoperatively (haematocrit [Hct] was accepted to a minimum level of 25%); the patients of group 2 (n = 50) were treated with postoperative autotransfusion (AT) of mediastinal shed blood and acceptance of NA. Group 3 (n = 50) contained control patients, not treated with NA or with AT (Hct was accepted to a minimum level of 30%). Patients of group 1 required 3.0 +/- 0.3 units of homologous blood products, but the patients of groups 2 and 3 received significantly more (p less than 0.01) units: 3.9 +/- 0.2 and 4.5 +/- 0.3 units. No donor blood products were needed in 36%, 9% and 5% of the patients in groups 1, 2 and 3 respectively. The net postoperative blood loss was similar in the groups: 1229 +/- 92 ml in group 1, 1098 +/- 74 ml in group 2 and 1243 +/- 72 ml in group 3. However, total blood loss (1982 +/- 135 ml), including the retransfused part (954 +/- 89 ml), was significantly larger (p less than 0.01) in group 2, than in groups 1 and 3.(ABSTRACT TRUNCATED AT 250 WORDS)
对150例行乳内动脉搭桥手术的患者进行回顾性研究，以评估两种血液保护技术在减少和预防使用同源血制品方面的疗效。根据术前血红蛋白（Hb）含量和体表面积对患者进行匹配，并分为三组：第1组（n = 50）患者术后接受正常血容量性贫血（NA）（血细胞比容[Hct]最低接受至25%）；第2组（n = 50）患者术后接受纵隔引流血自体输血（AT）并接受NA；第3组（n = 50）为对照组患者，未接受NA或AT治疗（Hct最低接受至30%）。第1组患者需要3.0±0.3单位的同源血制品，但第2组和第3组患者接受的单位数明显更多（p<0.01）：分别为3.9±0.2单位和4.5±0.3单位。第1、2、3组分别有36%、9%和5%的患者无需输注异体血制品。三组术后净失血量相似：第1组为1229±92 ml，第2组为1098±74 ml，第3组为1243±72 ml。然而，第2组的总失血量（1982±135 ml），包括回输部分（954±89 ml），明显大于第1组和第3组（p<0.01）。（摘要截断于250字）
