LeGrys V A
Division of Clinical Laboratory Science, University of North Carolina at Chapel Hill 27599.
Clin Lab Sci. 1992 Nov-Dec;5(6):354-7.
Variations in sweat chloride tests were analyzed. A total of 1,806 sweat test results were analyzed for intra-assay and inter-assay variation in sweat chloride concentration and sweat weight. The mean and standard deviation of sweat chloride determinations for the negative population was 11.63 mmol/L (7.20 s.d.); for the borderline population was 50.01 mmol/L (6.27 s.d.); and for the positive population was 96.75 mmol/L (s.d. = 13.81). The percent of sweat tests that were negative was 86.77, borderline, 3.82, and positive, 9.41. The variation, represented as the standard deviation, between bilateral sweat chloride values on the same patient for negative results is 10.23 and for positive results is 14.60. The average variation within a patient with regard to sweat weight is 19%. Clinical laboratory scientists can use this information in assessing their own quality assurance procedures and patient results.
分析了汗液氯化物检测的变异情况。共分析了1806份汗液检测结果，以评估汗液氯化物浓度和汗液重量的批内和批间变异。阴性人群汗液氯化物测定的均值和标准差分别为11.63 mmol/L（标准差7.20）；临界人群为50.01 mmol/L（标准差6.27）；阳性人群为96.75 mmol/L（标准差 = 13.81）。阴性汗液检测的百分比为86.77%，临界为3.82%，阳性为9.41%。同一患者双侧汗液氯化物值之间的变异（以标准差表示），阴性结果为10.23，阳性结果为14.60。患者汗液重量的平均变异为19%。临床实验室科学家可利用这些信息评估自身的质量保证程序和患者检测结果。
