Johnson M, Cane R D
University of South Florida College of Medicine, Tampa.
J Crit Illn. 1992 Jun;7(6):969-73.
Inverse ratio ventilation (IRV) differs from other ventilatory techniques in that it employs a prolonged inspiratory time. In theory, pressure-control IRV allows you to maintain ventilation and oxygenation with lower peak airway and end-expiratory pressures; this may reduce the potential for lung damage secondary to shearing forces. Consider pressure-control IRV for patients with acute lung disease characterized by low lung compliance, diffuse microatelectasis, and increased intrapulmonary shunting. Currently, the chief limitation of this technique is that the patient cannot breathe spontaneously during its use. The best inspiratory to expiratory ratio is the shortest inspiratory time that improves oxygenation with minimal hemodynamic compromise; depression of cardiac output will negate any potential improvement in arterial oxygenation.
反比通气(IRV)与其他通气技术的不同之处在于它采用延长的吸气时间。理论上,压力控制反比通气能让你在较低的气道峰压和呼气末压力下维持通气和氧合;这可能会降低因剪切力导致肺损伤的可能性。对于具有低肺顺应性、弥漫性微小肺不张和肺内分流增加等特征的急性肺疾病患者,可考虑采用压力控制反比通气。目前,该技术的主要局限性在于使用过程中患者无法自主呼吸。最佳吸呼比是能在对血流动力学影响最小的情况下改善氧合的最短吸气时间;心输出量降低会抵消动脉氧合的任何潜在改善。