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氦氖激光对大鼠实验性结肠吻合口愈合的组织学影响。

Histological effects of He:Ne laser on the healing of experimental colon anastomoses in the rat.

作者信息

Asencio-Arana F, Torres-Gil V, Soriano F M, Perez-Sarrio R

机构信息

Hospital Insalud, Denia Alicante, Spain.

出版信息

J Clin Laser Med Surg. 1990 Apr;8(2):27-33.

PMID:10148949
Abstract

Despite technical advances, the incidence of anastomotic leaks in elective colorectal surgery remains around 14%. Recent studies suggest that the use of low-energy lasers may enhance wound healing in different tissues in a selective, nondestructive manner. Based on these findings we have attempted to provide experimental background on the histological effects of He:Ne laser during the early stages of healing in 70 colonic anastomoses performed on rats. The irradiation of the anastomoses by two doses of 3.6 J/cm2 produces an increase in the populations of round cells and fibroblasts of the scar tissue, an increase in new vessel formation, and a significant improvement in epithelialization. This suggests that the irradiation of colonic wounds with He:Ne lasers can result in an enhancement of healing.

摘要

尽管技术有所进步,但择期结直肠手术中吻合口漏的发生率仍约为14%。最近的研究表明,使用低能量激光可能以一种选择性、非破坏性的方式促进不同组织的伤口愈合。基于这些发现,我们试图为70例大鼠结肠吻合口愈合早期氦氖激光的组织学效应提供实验依据。用两剂3.6 J/cm²对吻合口进行照射,可使瘢痕组织中的圆形细胞和成纤维细胞数量增加,新血管形成增加,上皮化显著改善。这表明用氦氖激光照射结肠伤口可促进愈合。

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