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一种用于对未受束缚动物的通气进行长期测量的体积描记器。

A plethysmograph for long-term measurements of ventilation in unrestrained animals.

作者信息

Jacky J P

出版信息

J Appl Physiol Respir Environ Exerc Physiol. 1978 Oct;45(4):644-7. doi: 10.1152/jappl.1978.45.4.644.

DOI:10.1152/jappl.1978.45.4.644
PMID:101497
Abstract

An apparatus for quantitative measurement of ventilation in unrestrained small animals is described. The subject rests in an environmental chamber, and respiration is indicated by barometric pressure oscillations proportional to tidal volume. The chamber is purged continuously at a relatively high flow rate during studies. Thus, CO2 does not accumulate and long-term measurement can proceed without interruption. Respiratory control studies are especially facilitated since different gas mixtures can be rapidly passed through the chamber. An electronic device also is described which automatically calculates expired minute volumes (VE) from the pressure signal obtained from the plethysmograph.

摘要

本文描述了一种用于定量测量不受束缚的小动物通气的装置。实验对象置于环境舱中,呼吸通过与潮气量成比例的气压振荡来指示。在研究过程中,环境舱以相对较高的流速持续换气。因此,二氧化碳不会积聚,长期测量可以不间断地进行。由于不同的气体混合物可以快速通过环境舱,呼吸控制研究尤其便利。本文还描述了一种电子设备,它能根据从体积描记器获得的压力信号自动计算呼出分钟通气量(VE)。

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