Itoh Y, Miura T, Katayama T, Haneishi T, Arai M
J Antibiot (Tokyo). 1978 Sep;31(9):834-7. doi: 10.7164/antibiotics.31.834.
Physico-chemical characterization of enaminomycins revealed that these antibiotics are new members of the epoxy quinone family. From elementary analysis and mass spectroscopic measurements the molecular formulae of enaminomycins A, B and C appear to be C7H5NO5, C10H11N06 and C7H7NO5, respectively. They are very unique in their chemical properties, possessing various functions, such as epoxy, primary amine and carboxylic acid, in their small structural units. Enaminomycin A, the most potent component, has activity against Gram-positive and Gram-negative bacteria and shows cytostatic effect on L1210 mouse leukemia cells in vitro, but enaminomycins B and C are only weakly active against Gram-positive and Gram-negative bacteria.
对烯胺霉素的物理化学特性分析表明，这些抗生素是环氧醌家族的新成员。通过元素分析和质谱测量，烯胺霉素A、B和C的分子式分别似乎为C7H5NO5、C10H11N06和C7H7NO5。它们在化学性质上非常独特，在其小结构单元中具有多种功能，如环氧基、伯胺和羧酸。烯胺霉素A是最有效的成分，对革兰氏阳性菌和革兰氏阴性菌均有活性，并且在体外对L1210小鼠白血病细胞表现出细胞抑制作用，但烯胺霉素B和C对革兰氏阳性菌和革兰氏阴性菌的活性较弱。
