[Sensitizing properties of strains of stpahylococci differing in toxigenicity in the immediate hypersensitivity reaction].

The author presents the results of studies on the effect of staphylococcus toxin formation on the origination of allergic reaction. Staph. aureus strains, active producers of the alpha- and gamma-hemolysin, leukocidin, and Staph. epidermidis strains possessing no pathogenicity signs (a total of 8 strains) were used for the sensitization. Guinea pigs and rabbits served for the reproduction of anaphylactic shock and passive skin anaphylaxis after Ovary. Toxigenic properties of the strain were not the dominating factor in the formation of an allergic reaction of the organism. Immediate sensitization reaction occurred in the animals in response to the toxigenic and nontoxigenic strains not only after the administration of a reacting dose of homologous, but also of other strains of different toxigenicity. Sensitization reaction with Staph. aureus strains was more pronounced. Sensitization of the organism with Staph. epidermidis strains (possessing no pathogenicity signs) is also possible.