Faktorich E G, Tucker N, O'Brien J M
Department of Ophthalmology, University of California, San Francisco, USA.
Curr Opin Ophthalmol. 1994 Oct;5(5):45-52.
Thyroid ophthalmopathy, idiopathic orbital inflammation, and orbital infection can occasionally demonstrate overlapping clinical features. It is essential to distinguish between these processes because appropriate treatments are distinct in each case. In the past year, the pathophysiology of thyroid ophthalmopathy has been the topic of many reports. Orbital inflammation, particularly the fibrotic form, has been recognized to represent a distinct disease entity that may require more specifically directed treatment. In some cases cytotoxic therapies may be indicated. Orbital infection, particularly in the setting of orbital abscess, may be treated conservatively with antibiotic therapy and observation or more aggressively with surgical drainage procedures. In several recent studies, appropriate management of such infectious processes appears to be related to patient age, as well as to the specific clinical pattern of presentation.
甲状腺眼病、特发性眼眶炎症和眼眶感染偶尔会表现出重叠的临床特征。区分这些病症至关重要,因为每种情况的适当治疗方法都不同。在过去一年里,甲状腺眼病的病理生理学一直是许多报告的主题。眼眶炎症,尤其是纤维化形式,已被认为是一种独特的疾病实体,可能需要更具针对性的治疗。在某些情况下,可能需要使用细胞毒性疗法。眼眶感染,尤其是在眼眶脓肿的情况下,可采用抗生素治疗并观察进行保守治疗,或采用手术引流程序进行更积极的治疗。在最近的几项研究中,此类感染性病症的适当管理似乎与患者年龄以及具体的临床表现模式有关。