Klintworth G K, Damms T
Duke University Medical Center, Durham, North Carolina, USA.
Curr Opin Ophthalmol. 1995 Aug;6(4):44-56. doi: 10.1097/00055735-199508000-00009.
Knowledge about keratoconus (KC) and the corneal dystrophies continues to advance at a steady pace in view of the wide interest in these topics to basic scientists and clinical ophthalmologists. As in the past the articles on KC outnumber those on all of the other corneal dystrophies combined. Major advances have been made mainly regarding several specific corneal dystrophies, but KC remains a perplexing disorder with many unanswered questions. As we learn more and more about the corneal dystrophies from genetic linkage analyses and molecular biological techniques it will eventually be possible to understand the fundamental defect that causes these conditions.
鉴于基础科学家和临床眼科医生对圆锥角膜(KC)和角膜营养不良这些课题广泛感兴趣,相关知识正持续稳步地向前发展。和过去一样,关于KC的文章数量超过了所有其他角膜营养不良文章数量的总和。主要进展主要集中在几种特定的角膜营养不良方面,但KC仍然是一种令人困惑的疾病,存在许多未解答的问题。随着我们通过基因连锁分析和分子生物学技术对角膜营养不良了解得越来越多,最终将有可能理解导致这些病症的根本缺陷。