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角膜营养不良和圆锥角膜。

Corneal dystrophies and keratoconus.

作者信息

Klintworth G K, Damms T

机构信息

Duke University Medical Center, Durham, North Carolina, USA.

出版信息

Curr Opin Ophthalmol. 1995 Aug;6(4):44-56. doi: 10.1097/00055735-199508000-00009.

DOI:10.1097/00055735-199508000-00009
PMID:10150882
Abstract

Knowledge about keratoconus (KC) and the corneal dystrophies continues to advance at a steady pace in view of the wide interest in these topics to basic scientists and clinical ophthalmologists. As in the past the articles on KC outnumber those on all of the other corneal dystrophies combined. Major advances have been made mainly regarding several specific corneal dystrophies, but KC remains a perplexing disorder with many unanswered questions. As we learn more and more about the corneal dystrophies from genetic linkage analyses and molecular biological techniques it will eventually be possible to understand the fundamental defect that causes these conditions.

摘要

鉴于基础科学家和临床眼科医生对圆锥角膜(KC)和角膜营养不良这些课题广泛感兴趣,相关知识正持续稳步地向前发展。和过去一样,关于KC的文章数量超过了所有其他角膜营养不良文章数量的总和。主要进展主要集中在几种特定的角膜营养不良方面,但KC仍然是一种令人困惑的疾病,存在许多未解答的问题。随着我们通过基因连锁分析和分子生物学技术对角膜营养不良了解得越来越多,最终将有可能理解导致这些病症的根本缺陷。

相似文献

1
Corneal dystrophies and keratoconus.角膜营养不良和圆锥角膜。
Curr Opin Ophthalmol. 1995 Aug;6(4):44-56. doi: 10.1097/00055735-199508000-00009.
2
Corneal dystrophies and keratoconus.角膜营养不良和圆锥角膜。
Curr Opin Ophthalmol. 1996 Aug;7(4):71-82. doi: 10.1097/00055735-199608000-00013.
3
Bilateral progressive essential iris atrophy and keratoconus with coincident features of posterior polymorphous dystrophy: a case report and proposed pathogenesis.双侧进行性原发性虹膜萎缩合并圆锥角膜及后多形性营养不良的特征:一例报告及发病机制探讨
Cornea. 1992 May;11(3):255-61.
4
[Update on corneal dystrophies: new insights following first publication of the IC3D classification].[角膜营养不良的最新进展:IC3D分类首次发表后的新见解]
Klin Monbl Augenheilkd. 2014 Jun;231(6):611-8. doi: 10.1055/s-0034-1368534. Epub 2014 Jun 18.
5
Familial cases of keratoconus associated with posterior polymorphous dystrophy.与后多形性营养不良相关的圆锥角膜家族病例。
Am J Ophthalmol. 1994 Aug 15;118(2):256-7. doi: 10.1016/s0002-9394(14)72911-3.
6
Keratoconus associated with corneal endothelial dystrophy.圆锥角膜合并角膜内皮营养不良。
Cornea. 1990 Oct;9(4):299-304.
7
Posterior polymorphous dystrophy associated with posterior amyloid degeneration of the cornea.
Am J Ophthalmol. 1999 Jan;127(1):86-8. doi: 10.1016/s0002-9394(98)00276-1.
8
Keratoconus and bilateral lattice-granular corneal dystrophies.
Cornea. 1992 Jul;11(4):343-50. doi: 10.1097/00003226-199207000-00013.
9
[Light and electron microscopic study of gelatinous drop-like corneal dystrophy with deeper stromal involvement].伴有深层基质受累的胶样滴状角膜营养不良的光镜和电镜研究
Nippon Ganka Gakkai Zasshi. 1988 Nov;92(11):1744-57.
10
Bilateral circumscribed posterior keratoconus.双侧局限性后圆锥角膜
J Am Optom Assoc. 1999 Sep;70(9):581-6.

引用本文的文献

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In Vivo Evaluation of Corneal Biomechanics Following Cross-Linking Surgeries Using Optical Coherence Elastography in a Rabbit Model of Keratoconus.在圆锥角膜兔模型中使用光学相干弹性成像技术对交联手术后角膜生物力学进行的体内评估。
Transl Vis Sci Technol. 2024 Feb 1;13(2):15. doi: 10.1167/tvst.13.2.15.
2
Crosslinking vs. Observation in Fellow Eyes of Keratoconus Patients.圆锥角膜患者对侧眼的交联术与观察对比
J Ophthalmol. 2022 Jun 1;2022:4661392. doi: 10.1155/2022/4661392. eCollection 2022.
3
Pathogenesis of keratoconus: NRF2-antioxidant, extracellular matrix and cellular dysfunctions.
圆锥角膜的发病机制:NRF2-抗氧化剂、细胞外基质和细胞功能障碍。
Exp Eye Res. 2022 Jun;219:109062. doi: 10.1016/j.exer.2022.109062. Epub 2022 Apr 3.
4
Transcriptomic and Immunohistochemical Analysis of Progressive Keratoconus Reveal Altered WNT10A in Epithelium and Bowman's Layer.转录组学和免疫组织化学分析进展性圆锥角膜显示上皮和Bowman 层中 WNT10A 的改变。
Invest Ophthalmol Vis Sci. 2021 May 3;62(6):16. doi: 10.1167/iovs.62.6.16.
5
Corneal cross-linking (CXL) combined with refractive surgery for the comprehensive management of keratoconus: CXL plus.角膜交联术(CXL)联合屈光手术综合治疗圆锥角膜:CXL增强术
Indian J Ophthalmol. 2020 Dec;68(12):2757-2772. doi: 10.4103/ijo.IJO_1841_20.
6
RNA sequencing of corneas from two keratoconus patient groups identifies potential biomarkers and decreased NRF2-antioxidant responses.对两个圆锥角膜患者群体的角膜进行 RNA 测序,鉴定出潜在的生物标志物和 NRF2 抗氧化反应的降低。
Sci Rep. 2020 Jun 18;10(1):9907. doi: 10.1038/s41598-020-66735-x.
7
Combined Protocols for Corneal Collagen Cross-Linking with Photorefractive Surgery for Refractive Management of Keratoconus: Update on Techniques and Review of Literature.角膜胶原交联联合屈光手术治疗圆锥角膜屈光不正的联合方案:技术更新与文献综述
Ophthalmol Ther. 2019 Oct;8(Suppl 1):15-31. doi: 10.1007/s40123-019-00210-3. Epub 2019 Oct 11.
8
Familial association of keratoconus and granular corneal dystrophy: The familial case series.圆锥角膜与颗粒状角膜营养不良的家族关联:家族病例系列
North Clin Istanb. 2018 Sep 4;6(2):176-183. doi: 10.14744/nci.2018.08860. eCollection 2019.
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Integrated Stress Response and Decreased ECM in Cultured Stromal Cells From Keratoconus Corneas.整合应激反应和角膜营养不良基质细胞中细胞外基质的减少。
Invest Ophthalmol Vis Sci. 2018 Jun 1;59(7):2977-2986. doi: 10.1167/iovs.18-24367.
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Pathophysiology of Keratoconus: What Do We Know Today.圆锥角膜的病理生理学:我们如今了解到了什么。
Open Ophthalmol J. 2017 Jul 31;11:252-261. doi: 10.2174/1874364101711010252. eCollection 2017.