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A comparison of serum concentrations of penicillin after intramuscular injection and subcutaneous and deep injection into the dewlap in cattle.牛肌肉注射、皮下注射及颈部垂皮深部注射后血清青霉素浓度的比较。
Acta Vet Scand. 1976;17(4):495-500. doi: 10.1186/BF03547905.
2
Benzathine penicillin G and procaine penicillin G in piglets: comparison of intramuscular and subcutaneous injection.苄星青霉素G和普鲁卡因青霉素G在仔猪中的应用：肌肉注射与皮下注射的比较
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Serum and subcutaneous chamber fluid dynamics of penicillins after single large parenteral doses.单次大剂量肠胃外给药后青霉素的血清及皮下腔隙液动力学
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Influence of injection site on the absorption of benzylpenicillin sodium in the dromedary.注射部位对单峰驼体内青霉素钠吸收的影响。
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[Concentration of penicillin and tetracycline in lymph of cattle during intramuscular and intracutaneous administration].[肌肉注射和皮内注射时青霉素和四环素在牛淋巴中的浓度]
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Penicillin concentrations in serum, milk, and urine following intramuscular and subcutaneous administration of increasing doses of procaine penicillin G in lactating dairy cows.泌乳奶牛肌肉注射和皮下注射递增剂量普鲁卡因青霉素G后血清、乳汁和尿液中的青霉素浓度。
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引用本文的文献

1
A comparison of the oxytetracycline preparations Aquacycline and Terramycin 100 with regard to absorption characteristics, local tissue reactions and residues following dewlap injections in calves.土霉素制剂水四环素和土霉素100在犊牛颈部垂皮注射后的吸收特性、局部组织反应及残留的比较
Acta Vet Scand. 1986;27(3):361-8. doi: 10.1186/BF03548150.

本文引用的文献

1
Absorption of drugs from subcutaneous connective tissue.药物从皮下结缔组织的吸收。
Pharmacol Rev. 1961 Sep;13:441-64.
2
Therapeutic serum concentrations of penicillin.青霉素的治疗血清浓度。
J Am Vet Med Assoc. 1971 Sep 15;159(6):757-9.
3
[Histologic changes after intramuscular injection with antibiotic preparations].[抗生素制剂肌肉注射后的组织学变化]
Nord Vet Med. 1973 Apr;24(4):181-5.
4
A residue study and comparison of penicillin and dihydrostreptomycin concentrations after intramuscular and subcutaneous administration in cattle.
J Am Vet Med Assoc. 1971 Mar 15;158(6):776-9.

牛肌肉注射、皮下注射及颈部垂皮深部注射后血清青霉素浓度的比较。

A comparison of serum concentrations of penicillin after intramuscular injection and subcutaneous and deep injection into the dewlap in cattle.

出版信息

Acta Vet Scand. 1976;17(4):495-500. doi: 10.1186/BF03547905.

DOI:10.1186/BF03547905
PMID:1015482
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8383940/
Abstract

Using an aqueous solution of sodium benzyl penicillin as the model substance, a comparison was made in cattle between absorption after intramuscular injection, and after subcutaneous and deep injection into the dewlap. The duration of supposed therapeutically effective serum concentrations using the 2 dewlap routes was longer than for the intramuscular route, although maximum concentrations were lower. The applicability of injection into the dewlap, especially the subcutaneous route, is discussed in relation to intramuscular injection.

摘要

以苄青霉素钠水溶液作为模型物质，在牛身上比较了肌肉注射、皮下注射和颈部垂肉深部注射后的吸收情况。尽管通过颈部垂肉的两种注射途径所达到的血清最高浓度较低，但假定的治疗有效血清浓度持续时间比肌肉注射更长。结合肌肉注射，讨论了颈部垂肉注射尤其是皮下注射途径的适用性。