Silver A L, Eichorn A, Pickett G P
IPRO, Lake Success, NY 10042, USA.
Clin Perform Qual Health Care. 1996 Jan-Mar;4(1):14-7.
Hospital charts were reviewed to ascertain the frequency with which patients with human immunodeficiency virus (HIV)-associated Pneumocystis carinii pneumonia (PCP) were being managed in accordance with current guidelines or recommendations in New York State for the calendar year 1993. Comparisons were made between hospitals that are designated by the New York State Department of Health as comprehensive treatment centers--designated acquired immunodeficiency syndrome (AIDS) centers--and all other hospitals. For patients who had been on PCP prophylaxis before admission, 34% had documentation of positive histologic evidence for PCP infection during the studied hospitalization period. Of all patients not on PCP prophylaxis at the time of admission, 94% had at least one of the diagnostic tests for PCP done during the PCP hospitalization. Eighty-one percent of all patients had either pulse oximetry or an arterial blood gas determination. Seventy-seven percent of all patients with a PO2 equal to or less than 70 mm Hg received steroids. All eligible patients received one of nine possible treatment combinations, which included either single drug therapy, multiple drug therapy, or participation in a clinical trial. Sixteen percent of eligible patients had no documentation of receiving PCP medication at discharge. Proportions receiving diagnostic or treatment interventions were usually higher in designated AIDS centers than in non-designated AIDS centers.
查阅了医院病历,以确定1993年日历年中,纽约州感染人类免疫缺陷病毒(HIV)的卡氏肺孢子虫肺炎(PCP)患者按照现行指南或建议接受治疗的频率。在纽约州卫生部指定为综合治疗中心(指定获得性免疫缺陷综合征(AIDS)中心)的医院与所有其他医院之间进行了比较。对于入院前接受过PCP预防治疗的患者,34%在研究的住院期间有PCP感染阳性组织学证据的记录。在入院时未接受PCP预防治疗的所有患者中,94%在PCP住院期间至少进行了一项PCP诊断测试。所有患者中有81%进行了脉搏血氧饱和度测定或动脉血气测定。PO2等于或低于70 mmHg的所有患者中有77%接受了类固醇治疗。所有符合条件的患者接受了九种可能的治疗组合之一,包括单药治疗、多药治疗或参与临床试验。16%符合条件的患者在出院时没有接受PCP药物治疗的记录。指定AIDS中心接受诊断或治疗干预的比例通常高于非指定AIDS中心。