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婴儿早期发育迟缓及死亡与尿中高香草酸和香草扁桃酸升高有关。

Failure to thrive and death in early infancy associated with raised urinary homovanillic and vanillylmandelic acids.

作者信息

Hirschberger M, Kleinberg G

出版信息

Arch Dis Child. 1976 Dec;51(12):977-9. doi: 10.1136/adc.51.12.977.

DOI:10.1136/adc.51.12.977
PMID:1015852
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1546169/
Abstract

A case of failure to thrive in an infant with persistently raised urinary levels of homovanillic and vanillylmandelic acids is descirbed. No neural crest tumour was discovered at surgical exploration or at necropsy. The relation of this biochemical abnormality and failure to thrive is unclear.

摘要

描述了一例患有高香草酸和香草扁桃酸尿水平持续升高的婴儿生长发育迟缓的病例。在手术探查或尸检中均未发现神经嵴肿瘤。这种生化异常与生长发育迟缓之间的关系尚不清楚。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8280/1546169/1240b23f276b/archdisch00822-0081-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8280/1546169/1240b23f276b/archdisch00822-0081-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8280/1546169/1240b23f276b/archdisch00822-0081-a.jpg

相似文献

1
Failure to thrive and death in early infancy associated with raised urinary homovanillic and vanillylmandelic acids.婴儿早期发育迟缓及死亡与尿中高香草酸和香草扁桃酸升高有关。
Arch Dis Child. 1976 Dec;51(12):977-9. doi: 10.1136/adc.51.12.977.
2
Urinary 3-methoxy-4-hydroxyphenylacetic (homovanillic) and 3-methoxy-4-hydroxymandelic (vanillylmandelic) acids: gas-liquid chromatographic methods and experience with 13 cases of neuroblastoma.尿中3-甲氧基-4-羟基苯乙酸（高香草酸）和3-甲氧基-4-羟基扁桃酸（香草扁桃酸）：气液色谱法及13例神经母细胞瘤的经验
Clin Chem. 1977 Dec;23(12):2247-9.
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Direct determination of urinary vanillylmandelic acid and homovanillic acid by high-performance liquid chromatography on an anion-exchange column.采用阴离子交换柱高效液相色谱法直接测定尿香草扁桃酸和高香草酸。
J Chromatogr. 1984 Nov 28;311(2):369-74. doi: 10.1016/s0378-4347(00)84731-3.
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More on gas-liquid chromatographic determination of homovanillic and vanillylmandelic acids in urine from cases of neuroblastoma.神经母细胞瘤患者尿液中高香草酸和香草扁桃酸的气液色谱测定的更多内容。
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Assessment of the diurnal variations in urinary homovanillic and vanillylmandelic acid excretion for the diagnosis and follow-up of patients with neuroblastoma.评估尿中高香草酸和香草扁桃酸排泄的昼夜变化用于神经母细胞瘤患者的诊断和随访。
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Analysis of vanillylmandelic and homovanillic acids in urine using solid phase sample preparation and high pressure liquid chromatography with electrochemical detection.采用固相样品前处理和带电化学检测的高压液相色谱法分析尿液中的香草扁桃酸和高香草酸。
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Determination of homovanillic, isohomovanillic and vanillylmandelic acids in human urine by means of glass capillary gas-liquid chromatography with temperature-programmed electron-capture detection.采用程序升温电子捕获检测的玻璃毛细管气液色谱法测定人尿中的高香草酸、异高香草酸和香草扁桃酸。
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Serial studies of serum dopamine-B-hydroxylase and urinary vanillylmandelic and homovanillic acids in neuroblastoma.神经母细胞瘤患者血清多巴胺-β-羟化酶及尿香草扁桃酸和高香草酸的系列研究。
Med Pediatr Oncol. 1979;6(2):93-9. doi: 10.1002/mpo.2950060202.
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[Characteristics of urinary excretion of vanilmandelic and homovanillic acids in cases of neuroblastoma during therapy].[神经母细胞瘤治疗期间香草扁桃酸和高香草酸的尿排泄特征]
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Simple method for the determination of homovanillic acid and vanillylmandelic acid in urine by high-performance liquid chromatography.高效液相色谱法测定尿中高香草酸和香草扁桃酸的简易方法。
J Chromatogr. 1982 Jan 8;227(1):162-7. doi: 10.1016/s0378-4347(00)80366-7.

引用本文的文献

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Familial neurodegenerative disorder associated with raised urinary vanillylmandelic acid.与尿香草扁桃酸升高相关的家族性神经退行性疾病。
Arch Dis Child. 1978 Aug;53(8):682-3. doi: 10.1136/adc.53.8.682.

本文引用的文献

1
FAILURE TO THRIVE. A DIAGNOSTIC APPROACH.发育迟缓：一种诊断方法
Postgrad Med. 1964 Mar;35:270-8. doi: 10.1080/00325481.1964.11695049.
2
The child who will not thrive.无法茁壮成长的孩子。
Br J Clin Pract. 1963 May;17:291-6.
3
Urinary catecholamine excretion by healthy children. I. Daily excretion of dopamine, norepinephrine, epinephrine, and 3-methoxy-4-hydroxymandelic acid.健康儿童尿中儿茶酚胺的排泄。I. 多巴胺、去甲肾上腺素、肾上腺素和3-甲氧基-4-羟基扁桃酸的每日排泄量。
Pediatrics. 1967 Feb;39(2):252-7.
4
Failure to thrive: a study of 100 infants and children.发育迟缓：对100名婴幼儿及儿童的研究。
Clin Pediatr (Phila). 1970 Feb;9(2):96-9. doi: 10.1177/000992287000900214.
5
Excretion of catecholamine catabolites by normal children.
J Lab Clin Med. 1968 Oct;72(4):612-20.
6
Catecholamines and neurologic diseases (second of two parts).儿茶酚胺与神经系统疾病（两部分中的第二部分）
N Engl J Med. 1975 Aug 14;293(7):332-8. doi: 10.1056/NEJM197508142930705.