Ol'khovskaia I G, Kazantseva I A
Arkh Patol. 1976;38(11):39-45.
Results of histological studies of desmoid tumours of various localisation and determination of their mitotic regimen are presented. the mitotic regimen of nonrelapsing desmoids is characterized by an extremely low mitotic index (on the average 0.9 mitosis per 1000 cells), a normal ratio of phases of mitosis and by the presence of only individual pathological mitoses. In the group of relapsing desmoids the mitotic index on the average is 2.4%; the analysis of the percentage ratio of mitosis phases reveals predominance of metaphases, the frequency of pathological mitoses being increased. These changes apparently reflect the trend of these tumours towards the unlimited growth, which is confirmed by their clinical course.
本文展示了不同部位硬纤维瘤的组织学研究结果及其有丝分裂情况。非复发性硬纤维瘤的有丝分裂情况特点为有丝分裂指数极低(平均每1000个细胞中有0.9个有丝分裂),有丝分裂各期比例正常,且仅存在个别病理性有丝分裂。在复发性硬纤维瘤组中,平均有丝分裂指数为2.4%;对有丝分裂各期百分比的分析显示中期占优势,病理性有丝分裂的频率增加。这些变化显然反映了这些肿瘤无限生长的趋势,这在它们的临床病程中得到了证实。